Does paroxetine impair testicular functions and oxidative status in rats?
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چکیده
منابع مشابه
The effect of sertraline, paroxetine, fluoxetine and escitalopram on testicular tissue and oxidative stress parameters in rats.
INTRODUCTION The aim of this study was to evaluate the effect of selective serotonin reuptake inhibitors (SSRIs) on testicular tissue and serum malondialdehyde (MDA) levels in rats. MATERIALS AND METHODS A total of 40 male Wistar albino rats, 5.5-6 months old, were equally divided at random into five groups: group 1 was the control group, group 2 received sertraline 10mg/kg (p.o), group 3 was...
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Background: Ciprofloxacin was shown to have cytotoxic effects on testicular germ cells. Its mechanism of cytotoxic action is not fully understood. To investigate the possibility of the involvement of an oxidative stress induction in this mechanism, total antioxidant power (TAOP) in the testis was evaluated. Materials and Methods: A number of twenty four mature male NMRI mice were used.The anima...
متن کاملTesticular oxidative stress. Effects of experimental varicocele in adolescent rats.
OBJECTIVE This present study was undertaken to determine the levels of malondialdehyde (MDA), nitric oxide (NO) and total antioxidant status (TAS) in testes of adolescent rats with experimental bilateral varicocele and to determine the effects of oxidative stress on testis produced by varicocele. METHODS 6-week-old, male Wistar rats, weighing 146-334 g (228.37 +/- 41.34 g), were randomly allo...
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Objective Reproductive toxicity is a major challenge associated with aluminum (Al) exposure. No studies have evaluated the possible effects of curcumin (CUR) on Al-induced reproductive dysfunction. Therefore, this study investigated the effects of CUR treatment on Al-induced reproductive damage. MaterialsAndMethods In this experimental study, 40 male Wistar rats were allocated to five groups (N...
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Background: Acyclovir (ACV) is a synthetic purine nucleoside analog drived from guanosine. ACV possesses antiviral activity against Herpes Simplex Virus types 1 and 2 (HSV-1 and HSV-2 ), Varicella Zoster virus (VZV) , Epstein Barr virus (EBV) and Cytomegalovirus (CMV). ACV exert its effects by interfering with DNA synthesis,thus inhibiting viral replication. ACV is khown to be toxic to gonads,t...
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ژورنال
عنوان ژورنال: European Urology Open Science
سال: 2020
ISSN: 2666-1683
DOI: 10.1016/s2666-1683(20)32925-6